beta Catenin Antikörper
Kurzübersicht für beta Catenin Antikörper (ABIN4949463)
Target
Alle beta Catenin (CATNB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Chicken b-Catenin was used as the immunogen for the b-Catenin antibody.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Titration of the b-Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1-2 μg/mL,WB: 1-2 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the b-Catenin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Andere Bezeichnung
- Beta Catenin
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Hintergrund
- The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]
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Pathways
- Peptide Hormone Metabolism
Target
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